Sarissa Biomedical Translating biomedical research into everyday care

Sarissa Biomedical

Translating biomedical research into everyday care

Latest Articles

The Ledger Beside the Result: Counting the People a Diagnostic Test Never Reached
Public Health Surveillance

The Ledger Beside the Result: Counting the People a Diagnostic Test Never Reached

Diagnostic evaluations often report sensitivity and specificity as though the tested group were the whole population. This article argues for a population ledger beside the performance score, so commissioners, clinicians and health-tech companies can see who was never invited, never tested or never followed up.

The Second Pair of Hands: Consent, Custody and Communication in Proxy Home Testing
Diagnostics and Primary Care

The Second Pair of Hands: Consent, Custody and Communication in Proxy Home Testing

Home diagnostics are usually designed around a single capable user, yet many kits are completed by carers, relatives or care staff on behalf of someone else. This article sets out what UK providers and clinicians need to resolve on consent, sample custody, safeguarding and result communication when the person administering the test is not the person the result is about.

The Unopened Envelope: Auditing the Home Test Kits That Never Get Used
Diagnostics and Primary Care

The Unopened Envelope: Auditing the Home Test Kits That Never Get Used

Home diagnostic kits are ordered, delivered and then sometimes left unopened. This article examines why non-use is an invisible gap in UK diagnostic care, sets out a practical audit framework for providers, and argues that an unused kit should be treated as clinical signal rather than silent failure.

Measuring the Return Journey: A Round-Trip Standard for Community Diagnostics
Diagnostics and Primary Care

Measuring the Return Journey: A Round-Trip Standard for Community Diagnostics

Mobile units and community phlebotomy are often judged by how far they travel from a hospital. A more useful test of access is the whole round trip: whether a test is offered, reached, transported within its window and acted on. This article sets out a practical standard for commissioners and practice teams.

The Supported Lifetime: Making Diagnostic Device End-of-Life a Clinical Responsibility
Diagnostics and Primary Care

The Supported Lifetime: Making Diagnostic Device End-of-Life a Clinical Responsibility

Connected diagnostic devices are now part of routine UK care, yet their retirement is often treated as an IT or procurement afterthought. This article argues that end-of-life planning should be a clinical responsibility, with contracts, registers and migration pathways that protect patients rather than abandon them.

What the Kit Wasn't Looking For: Incidental Results in UK Home Diagnostics
Clinical Testing Literacy

What the Kit Wasn't Looking For: Incidental Results in UK Home Diagnostics

Home tests are designed around a single question, but they can return answers to questions nobody asked. This article sets out the consent, disclosure and follow-up obligations that incidental findings create for UK consumer kits and NHS-adjacent diagnostic services in 2026.

The Journey Is the Assay: Cold-Chain Accountability in UK Home Diagnostics
Diagnostics and Primary Care

The Journey Is the Assay: Cold-Chain Accountability in UK Home Diagnostics

Home-testing services are often judged on laboratory performance, yet the specimen's real test begins at the doorstep. This article examines how courier handoffs and winter temperatures can alter results, and what providers, commissioners and clinicians should verify before recommending a kit.

Reference Ranges Are Not Reassurance: Designing Lab Results for the NHS App
Clinical Testing Literacy

Reference Ranges Are Not Reassurance: Designing Lab Results for the NHS App

Direct access to laboratory results is now part of everyday UK care, but a PDF or portal entry rarely arrives with the context needed to interpret it. This article sets out a practical framework for clinicians and health-tech designers to present ranges, uncertainty and next steps without turning transparency into self-diagnosis.

The Scan You Paid For: Who Owns the Follow-Up?
Diagnostics and Primary Care

The Scan You Paid For: Who Owns the Follow-Up?

Private full-body MRI packages are producing incidental findings that arrive in general practice without a clear owner. This article sets out a practical handover and triage framework for UK clinicians, and the consent points private providers should make clear before anyone pays for imaging.

When Home and Clinic Readings Diverge: A Practical Reconciliation Framework for UK Clinicians
Clinical Testing Literacy

When Home and Clinic Readings Diverge: A Practical Reconciliation Framework for UK Clinicians

Home blood-pressure monitors, glucose meters and pulse oximeters increasingly produce numbers that disagree with clinic measurements. This article sets out a plain-English approach to validation, calibration drift, technique and traceability, and offers a clinician-facing framework for separating noise from device error and genuine clinical signal.

The Cheapest Tube in the Room: Rethinking Diagnostic Value Beyond Unit Price
Diagnostics and Primary Care

The Cheapest Tube in the Room: Rethinking Diagnostic Value Beyond Unit Price

A low unit price can conceal a costly diagnostic pathway. This analysis sets out a practical total-pathway cost model for UK commissioners and clinical teams, showing why the better buy is often the test that produces a timely, actionable result rather than the one with the smallest invoice.

The Unfinished Result: Making Diagnostic Follow-Up Accountable in UK Care
Diagnostics and Primary Care

The Unfinished Result: Making Diagnostic Follow-Up Accountable in UK Care

A diagnostic result is an intermediate event, not an endpoint. This article examines the last mile of testing in UK care: how abnormal findings are communicated, owned and safety-netted across primary and secondary care, and why digital portals and AI triage should be judged by closed-loop follow-up rather than result delivery alone.

Between the Needle and the Report: A Practical Map of the UK Blood Sample Pathway
Clinical Testing Literacy

Between the Needle and the Report: A Practical Map of the UK Blood Sample Pathway

A routine blood test is often described as a single event, yet it is a sequence of handoffs, checks and queues. This article maps the journey from GP surgery to laboratory report in 2026, showing where delays, rejections and interpretation gaps can emerge and what clinicians and patients can reasonably ask.

After the Launch: Post-Market Surveillance as Everyday Diagnostic Care
Diagnostics and Primary Care

After the Launch: Post-Market Surveillance as Everyday Diagnostic Care

A diagnostic or health-software product does not stop changing once it reaches routine care. This article examines how post-market problems surface in UK practice, what MHRA and NHS reporting routes require, and why a transparent correction can strengthen rather than undermine clinical trust.

The Address on the Sample Tube: Local Validation for Home Diagnostic Kits
Clinical Testing Literacy

The Address on the Sample Tube: Local Validation for Home Diagnostic Kits

A laboratory assay can be analytically sound and still make a poor home-testing pathway. This article sets out why local validation matters for at-home blood, saliva and urine kits in the UK, and offers a plain-English checklist for clinicians, commissioners and consumers.

The Ward Without Walls: Point-of-Care Testing in UK Care Homes
Clinical Testing Literacy

The Ward Without Walls: Point-of-Care Testing in UK Care Homes

Rapid tests in nursing homes could keep frail residents out of hospital and speed treatment. The barriers are less about the technology than about training, funding and governance.

Beyond the Checkbox: Making Digital Triage Safe in UK Primary Care
Diagnostics and Primary Care

Beyond the Checkbox: Making Digital Triage Safe in UK Primary Care

Digital triage and AI symptom checkers are now part of the NHS front door. They can manage demand and surface red flags, but they cannot ask the questions that make a clinical conversation safe. A practical framework for 2026.

Adoption by Design: Turning a Validated Diagnostic into Routine NHS Care
Diagnostics and Primary Care

Adoption by Design: Turning a Validated Diagnostic into Routine NHS Care

A diagnostic can perform well in study conditions and still fail to change care if the route into practice is never designed. This analysis sets out why NICE evaluation, ICB budget silos, pathway ownership and the missing business case remain the real adoption gate — and the questions innovators, clinicians and commissioners should ask in 2026.

When a Blood Test Looks Reassuring: Five Caveats for the Clinical Conversation
Clinical Testing Literacy

When a Blood Test Looks Reassuring: Five Caveats for the Clinical Conversation

A blood result is a measurement under conditions, not a verdict, and the conditions matter most when the number looks normal. This practical listicle sets out five interpretive traps — haemolysis, fasting status, reference-range drift, incidental findings and repeat-testing thresholds — with consultation scripts for explaining uncertainty without undermining useful testing.

The Alert Before the Symptom: Triaging Consumer Wearable Notifications in UK Practice
Public Health Surveillance

The Alert Before the Symptom: Triaging Consumer Wearable Notifications in UK Practice

Smartwatches and rings now generate cardiac and breathing notifications for people who feel entirely well, and a growing share of those people present to general practice or emergency departments holding a phone. This opinion piece examines the distance between a consumer signal and a clinical diagnosis, and offers parallel checklists for clinicians and patients.

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